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Anti-CLOCK Antibody (3L638)
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产品编号 TMAC-00896
别名 KIAA0334, hCLOCK, CLOCK_HUMAN, Clock protein, Clock homolog, Clock circadian regulator, CLOCK, Class E basic helix-loop-helix protein 8, Circadium Locomotor Output Cycles Kaput, Circadian Locomotor Output Cycles Kaput, Circadian locomoter output cycles protein kaput, Circadian locomoter output cycles kaput protein, bHLHe8
Anti-CLOCK Antibody (3L638) 是一种 Rabbit 抗体，靶向 CLOCK。Anti-CLOCK Antibody (3L638) 可用于 WB,ICC/IF,IHC,FCM。
Anti-CLOCK Antibody (3L638)
Anti-CLOCK Antibody (3L638)
还可以产品编号 TMAC-00896 别名 KIAA0334, hCLOCK, CLOCK_HUMAN, Clock protein, Clock homolog, Clock circadian regulator, CLOCK, Class E basic helix-loop-helix protein 8, Circadium Locomotor Output Cycles Kaput, Circadian Locomotor Output Cycles Kaput, Circadian locomoter output cycles protein kaput, Circadian locomoter output cycles kaput protein, bHLHe8
Anti-CLOCK Antibody (3L638) 是一种 Rabbit 抗体，靶向 CLOCK。Anti-CLOCK Antibody (3L638) 可用于 WB,ICC/IF,IHC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CLOCK Antibody (3L638) is a Rabbit antibody targeting CLOCK. Anti-CLOCK Antibody (3L638) can be used in WB,ICC/IF,IHC,FCM. |
| 别名 | KIAA0334, hCLOCK, CLOCK_HUMAN, Clock protein, Clock homolog, Clock circadian regulator, CLOCK, Class E basic helix-loop-helix protein 8, Circadium Locomotor Output Cycles Kaput, Circadian Locomotor Output Cycles Kaput, Circadian locomoter output cycles protein kaput, Circadian locomoter output cycles kaput protein, bHLHe8 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of CLOCK on MCF-7 (1) and PC-12 (2) cell using anti-CLOCK antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human fetal skeletal muscle tissue using anti-CLOCK antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded 2 colon tissue using anti-CLOCK antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-CLOCK antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CLOCK antibody. Counter stained with hematoxylin. 6. ICC staining CLOCK in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining CLOCK in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. Flow cytometric analysis of Hela cells with CLOCK antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). |
| 应用 | |
| 推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Biological timepieces called circadian clocks are responsible for the regulation of hormonal rhythms, sleep cycles and other behaviors. The superchiasmatic nucleus (SCN), which is located in the brain, was the first mammalian circadian clock to be discovered. Clock, a member of the Basic-helix-loop-helix-psp (bHLH-PAS) family of transcription factors, has also been identified as having circadian function. Mutations within the clock gene have been shown to increase the length of the endogenous period and To contain a loss of rhythmicity of circadian oscillations. Clock contains a DNA-binding domain, a protein dimerization domain and a glutamine-rich C-terminal region, which indicates transactivation ability. It has been speculated that Clock may regulation circadian rhythmicity in combination with Other proteins such as Per. Per is also a PAS-domain containing protein that exhibits circadian function. Highest expression of Clock is seen in the hypothalamus and the eye. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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