Name: ANXA2 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPK-00784
Price: 313 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

5 μg

¥ 313

现货

10 μg

¥ 498

现货

20 μg

¥ 793

3日内发货

50 μg

¥ 1,580

3日内发货

100 μg

¥ 2,660

现货

200 μg

¥ 4,790

5日内发货

500 μg

¥ 10,600

5日内发货

生物活性

产品描述	ANXA2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 39.6 kDa and the accession number is P07355.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	ANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis, and acts as a molecular switch to EGFR activation. ANXA2 expression is inversely correlated with cell sensitivity to gefitinib. Knockdown of ANXA2 expression in MDA-MB-231 cells increased the gefitinib induced cell death. When ANXA2 was overexpressed in MCF7 cells, the gefitinib induced cell death was decreased. Furthermore, the phosphorylation of ANXA2 at Tyr23 is negatively correlated with the sensitivity of TNBC to gefitinib.
种属	Human
表达系统	E. coli
标签	N-His
蛋白编号	P07355
蛋白构建	Ser2-Asp339
蛋白纯度	> 95% as determined by Tris-Bis PAGE
蛋白性状	Lyophilized powder/Solution
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization./Supplied as 0.22 μm filtered solution in PBS, 50mM L-arginine, 4mM DTT (pH 7.4).
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	PAP-IV, p36, LPC2DP36, LPC2D, Lipocortin II, LIP2PAP-IV, Chromobindin-8, CAL1H, ANXA2, ANX2L4, ANX2, Annexin II, Annexin A2
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	39.6 kDa (predicted) same as Tris-Bis PAGE result.
颜色	White
物理性状	Lyophilized powder

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

ANXA2 Protein, Human, Recombinant (His)

ANXA2 Protein, Human, Recombinant (His)

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