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TAC(TERT activator compound)是一种TERT(Telomerase reverse transcriptase)激活剂,能通过 MEK/ERK/AP-1 级联途径增强TERT的转录活性,在原代人细胞和自然衰老小鼠中促进端粒的合成,减少细胞衰老和炎症细胞因子,减轻神经炎症等等。
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TAC(TERT activator compound)是一种TERT(Telomerase reverse transcriptase)激活剂,能通过 MEK/ERK/AP-1 级联途径增强TERT的转录活性,在原代人细胞和自然衰老小鼠中促进端粒的合成,减少细胞衰老和炎症细胞因子,减轻神经炎症等等。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 347 | In stock | |
5 mg | ¥ 828 | In stock | |
10 mg | ¥ 1,490 | In stock | |
25 mg | ¥ 2,530 | In stock | |
50 mg | ¥ 3,790 | In stock | |
100 mg | ¥ 5,390 | In stock | |
200 mg | ¥ 7,380 | In stock | |
1 mL x 10 mM (in DMSO) | ¥ 892 | In stock |
TAC 相关产品
产品描述 | TAC (TERT activator compound) is a TERT (telomerase reverse transcriptase) activator that enhances TERT transcriptional activity through the MEK/ERK/AP-1 cascade pathway, promotes telomere synthesis in primary human cells and naturally aged mice, reduces cellular senescence and inflammatory cytokines, and alleviates neuroinflammation, among other effects. |
别名 | TERT activator-1, TERT activator compound |
分子量 | 331.77 |
分子式 | C14H12ClF2NO2S |
CAS No. | 666699-46-3 |
Smiles | O=S(=O)(NC1=CC=C(F)C(Cl)=C1)C=2C=C(C(F)=C(C2)C)C |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 80 mg/mL (241.13 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
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