购物车
- 全部删除
您的购物车当前为空
Anti-Phospho-p53 (Ser20) Polyclonal Antibody
还可以
产品编号 TMAC-02982
别名 p-p53 (Ser20), p-p53 (S20), p53 (p-Ser20), p53 (p-S20)
Anti-Phospho-p53 (Ser20) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-p53 (Ser20)。Anti-Phospho-p53 (Ser20) Polyclonal Antibody 可用于 WB。
Anti-Phospho-p53 (Ser20) Polyclonal Antibody
Anti-Phospho-p53 (Ser20) Polyclonal Antibody
还可以产品编号 TMAC-02982 别名 p-p53 (Ser20), p-p53 (S20), p53 (p-Ser20), p53 (p-S20)
Anti-Phospho-p53 (Ser20) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-p53 (Ser20)。Anti-Phospho-p53 (Ser20) Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,240 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-Phospho-p53 (Ser20) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p53 (Ser20). Anti-Phospho-p53 (Ser20) Polyclonal Antibody can be used in WB. |
| 别名 | p-p53 (Ser20), p-p53 (S20), p53 (p-Ser20), p53 (p-S20) |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse |
| 验证活性 | 1. Western blot analysis of extracts from Mouse brain tissue using p53 (Phospho-Ser20) Antibody TMAC-02982. The lane on the right is treated with the antigen-specific peptide. |
| 应用 | |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| 性状 | Liquid |
| 缓冲液 | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | Peptide sequence around phosphorylation site of Serine 20 (T-F-S(p)-D-L) derived from Human p53 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Actual: 53 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
SCI 文献
评论列表
预览
Related Tags: buy Anti-Phospho-p53 (Ser20) Polyclonal Antibody | purchase Anti-Phospho-p53 (Ser20) Polyclonal Antibody | Anti-Phospho-p53 (Ser20) Polyclonal Antibody cost | order Anti-Phospho-p53 (Ser20) Polyclonal Antibody | Anti-Phospho-p53 (Ser20) Polyclonal Antibody molecular weight
嗨！有任何问题？点我咨询
评论内容