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Anti-Syndecan-4 Antibody-PE (7T56)
还可以产品编号 TMAY-03438P
Anti-Syndecan-4 Antibody-PE (7T56) 是一种 PE-conjugated Rabbit 抗体，靶向 Syndecan-4。Anti-Syndecan-4 Antibody-PE (7T56) 可用于 FCM。
Anti-Syndecan-4 Antibody-PE (7T56)
Anti-Syndecan-4 Antibody-PE (7T56)
还可以产品编号 TMAY-03438P
Anti-Syndecan-4 Antibody-PE (7T56) 是一种 PE-conjugated Rabbit 抗体，靶向 Syndecan-4。Anti-Syndecan-4 Antibody-PE (7T56) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Syndecan-4 Antibody-PE (7T56) is a PE-conjugated Rabbit antibody targeting Syndecan-4. Anti-Syndecan-4 Antibody-PE (7T56) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 7T56 |
| 交叉反应 | Mouse |
| 验证活性 | Flow cytometric analysis of mouse SDC4 expression on mouse splenocytes. BABL/c splenocytes were stained with PE-conjugated anti-Mouse SDC4 and FITC-conjugated anti-Mouse CD3 (BD Pharmingen™ Cat. No.553061, left) or APC-conjugated anti-Mouse CD19 (BD Pharmingen™ Cat. No.550992, right). |
| 应用 | FCM |
| 推荐剂量 | 2 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Syndecan-4 / SDC4 (rM Syndecan-4 / SDC4; TMPY-02392; O35988; Met1-Val146) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in the phosphorylation of focal adhesion kinase (FAK) on Tyr397. Syndecan-4 plays roles in the formation of focal adhesions and stress fibers. The cytoplasmic domain of syndecan-4 interacts with several signalling and structural proteins, and both extracellular and cytoplasmic domains are necessary for regulated activation of associated transmembrane receptors. Syndecan-4/SDC4 is a heparan sulfate proteoglycan and works as a coreceptor for various growth factors. SDC4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization. Therefore, SDC4 may be a novel therapeutic target for preventing arterial restenosis after angioplasty. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Mouse Syndecan-4 / SDC4 protein (TMPY-02392) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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