规格

价格

库存

数量

5 μg

¥ 493

现货

10 μg

¥ 790

现货

20 μg

¥ 1,330

现货

50 μg

¥ 2,580

5日内发货

100 μg

¥ 5,170

5日内发货

生物活性

产品描述	TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with hHis and Fc tag. The predicted molecular weight is 57 kDa and the accession number is AAC39862.1.
生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulin mucin 1 (TIM-1), is a type of integral membrane glycoprotein. KIM-1 protein is widely expressed with the highest levels in the kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy, and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
种属	Human
表达系统	HEK293 Cells
标签	C-His, N-hFc
蛋白编号	AAC39862.1
蛋白构建	A DNA sequence encoding the mature form of human KIM1 extracellular domain (AAC39862.1) (Ser 21-Gly 290) was fused with a polyhistidine tag at the C-terminus and the Fc region of human IgG1 at the N-terminus. Predicted N terminal: Glu
蛋白纯度	> 92 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	Reconstituted with sterile deionized water to 0.2 mg/mL. Reconstitution conditions may vary depending on the lot.
别名	TIMD-1, TIMD1, TIM-1, TIM1, TIM, KIM-1, KIM1, hepatitis A virus cellular receptor 1, HAVCR-1, HAVCR, HACVR, CD365
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	57 kDa (predicted); 120-140 kDa (reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His & hFc)

TIM-1/KIM-1/HAVCR1 Protein, Human, Recombinant (His & hFc)

产品介绍

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