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Anti-GRIK3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GRIK3。Anti-GRIK3 Polyclonal Antibody 可用于 FCM。
Anti-GRIK3 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GRIK3。Anti-GRIK3 Polyclonal Antibody 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-GRIK3 Polyclonal Antibody is a Rabbit antibody targeting GRIK3. Anti-GRIK3 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep) |
| 验证活性 | Blank control: MCF7. Primary Antibody (green line): Rabbit Anti-GRIK3 antibody (TMAB-06770) Dilution: 1 μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG. Secondary Antibody: Goat anti-rabbit IgG-PE Dilution: 2 μg /test. Protocol The cells were incubated in 5% BSA to block non-specific protein-protein interactions for 30 min at at room temperature. Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed. |
| 应用 | FCM |
| 推荐剂量 | FCM: 2μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human GRIK3/GLR7 |
| 抗原种属 | Human |
| 基因名称 | GRIK3 |
| 基因ID | |
| 蛋白名称 | Glutamate receptor ionotropic, kainate 3 |
| Uniprot ID | |
| 功能 | Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds domoate > kainate >> L-glutamate = quisqualate >> AMPA = NMDA. |
| 分子量 | Theoretical: 100 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |