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Anti-Phospho-ADRB2 (Ser346) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-ADRB2 (Ser346)。Anti-Phospho-ADRB2 (Ser346) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。
Anti-Phospho-ADRB2 (Ser346) Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 Phospho-ADRB2 (Ser346)。Anti-Phospho-ADRB2 (Ser346) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-Phospho-ADRB2 (Ser346) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-ADRB2 (Ser346). Anti-Phospho-ADRB2 (Ser346) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Rat (predicted:Mouse,Dog,Horse,Sheep) |
| 应用 | IHC-PIHC-FrIFFCM |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 2μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Note=Colocalizes with VHL at the cell membrane. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L type calcium channel Ca(V)1.2. This receptor channel complex also contains a G protein, an adenylyl cyclase, cAMP dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor. This gene contains no introns in either its coding or untranslated sequences. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. Expression of the beta 2 Adrenergic Receptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel. |
| 免疫原 | KLH conjugated Synthesised phosphopeptide: human ADRB2 around the phosphorylation site of Ser346 |
| 抗原种属 | Human |
| 基因名称 | ADRB2 |
| 基因ID | |
| 蛋白名称 | beta-2 adrenergic receptor |
| Uniprot ID | |
| 功能 | Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine. |
| 分子量 | Theoretical: 46 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |