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Anti-CD84 Antibody (4Q464)

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产品编号 TMAY-00253

别名 CD84 molecule

Anti-CD84 Antibody (4Q464) 是一种 Mouse 抗体，靶向 CD84。Anti-CD84 Antibody (4Q464) 可用于 ELISA(Det)。

Anti-CD84 Antibody (4Q464)

Anti-CD84 Antibody (4Q464)

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产品编号 TMAY-00253 别名 CD84 molecule

Anti-CD84 Antibody (4Q464) 是一种 Mouse 抗体，靶向 CD84。Anti-CD84 Antibody (4Q464) 可用于 ELISA(Det)。

规格价格库存数量
20 μL
¥ 585
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100 μL
¥ 1,694
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产品介绍

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产品描述
Anti-CD84 Antibody (4Q464) is a Mouse antibody targeting CD84. Anti-CD84 Antibody (4Q464) can be used in ELISA(Det).
别名CD84 molecule
Ig Type
Mouse IgG1
克隆号
4Q464
交叉反应
Human
特异性
Human CD84
应用ELISA(Det)
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD84 (rh CD84; TMPY-00715; NP_003865.1; Met1-Gly225). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The CD2 family receptors are type I transmembrane glycoproteins belonging to immunoglobulin (Ig) superfamily characterized by a membrane-proximal Ig constant 2 (C2) domain and a membrane-distal variable (V) domain that is responsible for ligand recognition. CD84, also known as LY9B and SLAMF5, is a homophilic member of the SLAM (signaling lymphocyte activation molecule) subfamily of the CD2 family. The SLAM family receptorsmediate signal transduction through the interaction of its ITSM (immunoreceptor tyrosine-based switch motifs) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2), and accordingly modulate both adaptive and innate immune responses. The CD84-CD84 interaction was independent of its cytoplasmic tail. Thus, CD84 is its own ligand and acts as a costimulatory molecule. CD84 is expressed on cells from almost all hematopoietic lineages and on CD34+ hematopoietic progenitor cells, suggesting that CD84 serves as a marker for committed hematopoietic progenitor cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human CD84 Protein (TMPY-00715)
抗原种属
Human
研究领域
ITIM/ITAM Immunoreceptors and Related Molecules
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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