Name: TNF alpha Protein, Ferret, Recombinant
Brand: TargetMol
SKU: TMPY-02226
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 820

6-8日内发货

10 μg

¥ 1,350

6-8日内发货

20 μg

¥ 2,630

5日内发货

生物活性

产品描述	TNF alpha Protein, Ferret, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is A3FBF1.
生物活性	Measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The EC50 for this effect is typically 5-30 pg/ml.
研究背景	Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & AntibodyCancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
种属	Ferret
表达系统	E. coli
标签	Tag Free
蛋白编号	A3FBF1
蛋白构建	A DNA sequence encoding the mature form of Ferret (Mustela putorius furo) TNFα (A3FBF1) (Val 77-Leu 233) was expressed, with an initial Met at the N-terminus. Predicted N terminal: Met
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	肿瘤坏死因子, tumor necrosis factor, TNF-α
内毒素	Please contact us for more information.

化学信息

分子量	17.3 kDa (predicted); 16 kDa (reducing conditions)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

TNF alpha Protein, Ferret, Recombinant

TNF alpha Protein, Ferret, Recombinant

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