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Anti-Polycystin 2 Polyclonal Antibody

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货号 TMAB-11630

Anti-Polycystin 2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Polycystin 2。Anti-Polycystin 2 Polyclonal Antibody 可用于 WB。

Anti-Polycystin 2 Polyclonal Antibody

Anti-Polycystin 2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-11630

Anti-Polycystin 2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Polycystin 2。Anti-Polycystin 2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-Polycystin 2 Polyclonal Antibody is a Rabbit antibody targeting Polycystin 2. Anti-Polycystin 2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Pig,Cow,Horse,Rabbit,Zebrafish)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein (Potential). Endoplasmic reticulum. Cell projection, cilium.
组织特异性Strongly expressed in ovary, fetal and adult kidney, testis, and small intestine. Not detected in peripheral leukocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Polycystin 2
抗原种属
Human
基因名称
PKD2
基因ID
蛋白名称
Polycystin-2
Uniprot ID
功能
Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Functions as a calcium permeable cation channel.
化学信息
分子量Theoretical: 106 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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