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Anti-ACVR2B Antibody (8V350)

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产品编号 TMAY-00495

Anti-ACVR2B Antibody (8V350) 是一种 Rabbit 抗体,靶向 ACVR2B。Anti-ACVR2B Antibody (8V350) 可用于 ELISA。

Anti-ACVR2B Antibody (8V350)

Anti-ACVR2B Antibody (8V350)

Rating icon 还可以
产品编号 TMAY-00495

Anti-ACVR2B Antibody (8V350) 是一种 Rabbit 抗体,靶向 ACVR2B。Anti-ACVR2B Antibody (8V350) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-ACVR2B Antibody (8V350) is a Rabbit antibody targeting ACVR2B. Anti-ACVR2B Antibody (8V350) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
8V350
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ACVR2B (rh ACVR2B ; TMPY-01051; NP_001097.2; Met1-Thr134).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of skeletal muscle growth, is regarded as a potential therapeutic target and binds to ACVR2B effectively, and to a lesser extent, to ACVR2A. The structure of human ACVR2B kinase domain in complex with adenine establishes the conserved bilobal architecture consistent with all other catalytic kinase domains. Haplotype structure at the ACVR2B and follistatin loci may contribute to interindividual variation in skeletal muscle mass and strength. Defects in ACVR2B are a cause of left-right axis malformations.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human ACVR2B Protein (TMPY-01051)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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