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Anti-ACVR2B Antibody (8V350) 是一种 Rabbit 抗体,靶向 ACVR2B。Anti-ACVR2B Antibody (8V350) 可用于 ELISA。
Anti-ACVR2B Antibody (8V350) 是一种 Rabbit 抗体,靶向 ACVR2B。Anti-ACVR2B Antibody (8V350) 可用于 ELISA。
产品描述 | Anti-ACVR2B Antibody (8V350) is a Rabbit antibody targeting ACVR2B. Anti-ACVR2B Antibody (8V350) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8V350 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human ACVR2B (rh ACVR2B ; TMPY-01051; NP_001097.2; Met1-Thr134). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | ACVR2A and ACVR2B are two activin type II receptors. ACVR2B is integral to the activin and myostatin signaling pathway. Ligands such as activin and myostatin bind to ACVR2A and ACVR2B. Myostatin, a negative regulator of skeletal muscle growth, is regarded as a potential therapeutic target and binds to ACVR2B effectively, and to a lesser extent, to ACVR2A. The structure of human ACVR2B kinase domain in complex with adenine establishes the conserved bilobal architecture consistent with all other catalytic kinase domains. Haplotype structure at the ACVR2B and follistatin loci may contribute to interindividual variation in skeletal muscle mass and strength. Defects in ACVR2B are a cause of left-right axis malformations. |
偶联 | Unconjugated |
免疫原 | Recombinant Human ACVR2B Protein (TMPY-01051) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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