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顶部产品介绍偶联与修饰储存和溶解信息计算器

Anti-Obinutuzumab Antibody (5T476)

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货号 TMAS-00061

别名 Gazyva

Anti-Obinutuzumab Antibody (5T476) 是一种 Mouse 抗体，靶向 Obinutuzumab。Anti-Obinutuzumab Antibody (5T476) 可用于 ELISA。

Anti-Obinutuzumab Antibody (5T476)

Anti-Obinutuzumab Antibody (5T476)

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Rating icon 还可以
货号 TMAS-00061 别名 Gazyva

Anti-Obinutuzumab Antibody (5T476) 是一种 Mouse 抗体，靶向 Obinutuzumab。Anti-Obinutuzumab Antibody (5T476) 可用于 ELISA。

规格价格库存数量
40 μg
¥ 1,609
5日内发货
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产品介绍

生物活性
产品描述
Anti-Obinutuzumab Antibody (5T476) is a Mouse antibody targeting Obinutuzumab. Anti-Obinutuzumab Antibody (5T476) can be used in ELISA.
别名Gazyva
Ig Type
IgG2a,κ
克隆号
5T476
特异性
The product is specific for Obinutuzumab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody Anti-Obinutuzumab Antibody (8M836) (TMAS-00062).
应用ELISA
推荐剂量
ELISA: 0.01-1 µg/ml
抗体种类
Monoclonal
宿主来源Mouse
纯化方式Protein A affinity column
性状Lyophilized. Reconstitute the lyophilized powder with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
缓冲液Lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
研究背景Obinutuzumab is a humanized anti-CD20 monoclonal antibody, originated by GlycArt Biotechnology AG and developed by Roche as a cancer treatment. It was approved under the trade name Gazyva by the US FDA in 2013, and as Gazyvaro by the EMA in Europe, for the treatment of chronic lymphocytic leukemia in combination with chemotherapy in treatment-naive patients, and as a second line treatment for follicular lymphoma. Obinutuzumab is a fully humanized monoclonal antibody that binds to an epitope on CD20 that partially overlaps with the epitope recognized by rituximab. Obinutuzumab binds to CD20 on B cells and causes these cells to be destroyed by engaging the adaptive immune system, directly activating intracellular apoptosis pathways, and activating the complement system.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin
可提供抗体种类
2
抗原信息
免疫原
Obinutuzumab
储存&溶解度
储存方式The lyophilized product store at -20°C or -80°C for 12 months. The reconstituted antibody can be stored at 2°C-8°C for 2-3 weeks or at -20°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储-20°C for 1 year

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