keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Enloplatin 是一种卡铂类似物,在治疗晚期卵巢癌有部分作用。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 530 | 现货 | ||
5 mg | ¥ 1,230 | 现货 | ||
10 mg | ¥ 1,830 | 现货 | ||
25 mg | ¥ 3,530 | 现货 | ||
50 mg | ¥ 4,800 | 现货 | ||
100 mg | ¥ 6,830 | 现货 | ||
500 mg | ¥ 13,700 | 现货 |
产品描述 | Enloplatin is a carboplatin analog that has a partial role in advanced ovarian cancer. |
靶点活性 | Tera (cells):7.2 µM |
体内活性 | Enloplatin (i.v. infusion; over 1.5 h; every 21 days), one patient had a partial response (6%; 95% CI 0-26%) lasting 2.8 months. The median survival was 9.4 months (95%; CI 5.1-19.7%). Neutropenia was the dose-limiting toxicity. Nephrotoxicity was manageable. Enloplatin is the major form of the free drug in plasma. However, 13.5 h after initiation of treatment, 85% of the drug in plasma is protein bound. Elimination of the drug is mainly renal.[1] |
分子量 | 481.4 |
分子式 | C13H22N2O5Pt |
CAS No. | 111523-41-2 |
keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (114.25 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.0773 mL | 10.3864 mL | 20.7727 mL | 51.9319 mL |
5 mM | 0.4155 mL | 2.0773 mL | 4.1545 mL | 10.3864 mL | |
10 mM | 0.2077 mL | 1.0386 mL | 2.0773 mL | 5.1932 mL | |
20 mM | 0.1039 mL | 0.5193 mL | 1.0386 mL | 2.5966 mL | |
50 mM | 0.0415 mL | 0.2077 mL | 0.4155 mL | 1.0386 mL | |
100 mM | 0.0208 mL | 0.1039 mL | 0.2077 mL | 0.5193 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Enloplatin 111523-41-2 Inhibitor inhibitor inhibit