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Anti-Dicer Antibody (7P583) 是一种 Mouse 抗体,靶向 Dicer。Anti-Dicer Antibody (7P583) 可用于 WB,ICC/IF。
Anti-Dicer Antibody (7P583) 是一种 Mouse 抗体,靶向 Dicer。Anti-Dicer Antibody (7P583) 可用于 WB,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-Dicer Antibody (7P583) is a Mouse antibody targeting Dicer. Anti-Dicer Antibody (7P583) can be used in WB,ICC/IF. |
| Ig Type | IgG2a |
| 克隆号 | 7P583 |
| 反应种属 | Human |
| 应用 | WBICC/IF |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-250 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cytoplasm. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010] |
| 基因名称 | DICER1 |
| 基因ID | |
| 蛋白名称 | Endoribonuclease Dicer |
| 功能 | Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |