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Anti-RAD23A Antibody (9Q812) 是一种 Rabbit 抗体,靶向 RAD23A。Anti-RAD23A Antibody (9Q812) 可用于 WB,FCM。
Anti-RAD23A Antibody (9Q812) 是一种 Rabbit 抗体,靶向 RAD23A。Anti-RAD23A Antibody (9Q812) 可用于 WB,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-RAD23A Antibody (9Q812) is a Rabbit antibody targeting RAD23A. Anti-RAD23A Antibody (9Q812) can be used in WB,FCM. |
| Ig Type | IgG |
| 克隆号 | 9Q812 |
| 反应种属 | Human (predicted:Mouse,Rat) |
| 应用 | WBFCM |
| 推荐剂量 | WB: 1:500-2000; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. |
| 免疫原 | A synthesized peptide: human RAD23A |
| 抗原种属 | Human |
| 基因名称 | RAD23A |
| 基因ID | |
| 蛋白名称 | UV excision repair protein RAD23 homolog A |
| Uniprot ID | |
| 功能 | Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC.Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome. |
| 分子量 | Theoretical: 40 kDa. Actual: 55 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |