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Anti-NRG1 Beta 1 Antibody (1T318)
还可以产品编号 TMAY-00060
Anti-NRG1 Beta 1 Antibody (1T318) 是一种 Mouse 抗体，靶向 NRG1 Beta 1。Anti-NRG1 Beta 1 Antibody (1T318) 可用于 WB。
Anti-NRG1 Beta 1 Antibody (1T318)
Anti-NRG1 Beta 1 Antibody (1T318)
还可以产品编号 TMAY-00060
Anti-NRG1 Beta 1 Antibody (1T318) 是一种 Mouse 抗体，靶向 NRG1 Beta 1。Anti-NRG1 Beta 1 Antibody (1T318) 可用于 WB。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-NRG1 Beta 1 Antibody (1T318) is a Mouse antibody targeting NRG1 Beta 1. Anti-NRG1 Beta 1 Antibody (1T318) can be used in WB. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 1T318 |
| 交叉反应 | Human |
| 验证活性 | Anti-NRG1-beta 1 mouse monoclonal antibody at 1:500Lane A: Human NRG1-beta1 (100ng) -Lane B: Human NRG1-alpha (100ng) -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Performed under reducing conditions. |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, a synthetic peptide corresponding to the center region of the human NRG1 isoform beta 1. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | A synthetic peptide corresponding to the center region of the human NRG1 isoform beta 1. |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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