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Anti-CEACAM6 Antibody (5G286)
还可以产品编号 TMAY-01220
Anti-CEACAM6 Antibody (5G286) 是一种 Mouse 抗体，靶向 CEACAM6。Anti-CEACAM6 Antibody (5G286) 可用于 ELISA。
Anti-CEACAM6 Antibody (5G286)
Anti-CEACAM6 Antibody (5G286)
还可以产品编号 TMAY-01220
Anti-CEACAM6 Antibody (5G286) 是一种 Mouse 抗体，靶向 CEACAM6。Anti-CEACAM6 Antibody (5G286) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-CEACAM6 Antibody (5G286) is a Mouse antibody targeting CEACAM6. Anti-CEACAM6 Antibody (5G286) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5G286 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CEACAM6 / CD66c (rhCEACAM6; TMPY-00971; NP_002474.4; Met 1-Gly 320). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6), also known as nonspecific crossreacting antigen (NCA) and CD66c, is one of seven human CEACAM family members within the immunoglobulin superfamily. It s a glycosylphosphatidylinositol-linked immunoglobulin superfamily member that is overexpressed in a variety of human cancers, including colon, breast and lung and is associated with tumourigenesis, tumour cell adhesion, invasion and metastasis. CEACAM6 is a unique mediator of migration and invasion of drug resistant oestrogen-deprived breast cancer cells, and this protein could be an important biomarker of metastasis. CEACAM6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CD66c protein (TMPY-00971) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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