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Anti-GDNF Antibody (7K481)

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Anti-GDNF Antibody (7K481)
产品编号 TMAC-01639

Anti-GDNF Antibody (7K481) 是一种 Rabbit 抗体,靶向 GDNF。Anti-GDNF Antibody (7K481) 可用于 WB,FCM。

Anti-GDNF Antibody (7K481)

Anti-GDNF Antibody (7K481)

Rating icon 还可以
Anti-GDNF Antibody (7K481)
产品编号 TMAC-01639

Anti-GDNF Antibody (7K481) 是一种 Rabbit 抗体,靶向 GDNF。Anti-GDNF Antibody (7K481) 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-GDNF Antibody (7K481) is a Rabbit antibody targeting GDNF. Anti-GDNF Antibody (7K481) can be used in WB,FCM.
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of GDNF on HepG2 cell using anti-GDNF antibody at 1/1,000 dilution.
2. Flow cytometric analysis of SH-SY5Y cells with GDNF antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Glial cell line-derived neurotrophic factor (GDNF) has been identified as a potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons. GDNF is a glycosylated, disulfide-bonded homodimer and is a distantly related member of the TGFβ superfamily of growth regulatory ligands. GDNF contains the seven conserved cysteine residues in the same relative spacing characteristic of all members of the TGFβ superfamily. In embryonic midbrain cultures, GDNF promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. On the basis of these findings, it has been suggested that GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 24 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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