购物车
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部相关产品产品介绍化学信息储存和溶解信息计算器

Sarafloxacin hydrochloride

一键复制产品信息
Rating icon 很棒

纯度: 97.44%

货号 T1107Cas号 91296-87-6

别名 盐酸沙拉沙星, Sarafloxacin HCl, A-56620 HCl, A-56620 (hydrochloride)

Sarafloxacin hydrochloride (A-56620 (hydrochloride)) 是一种抗菌化合物。

Sarafloxacin hydrochloride
其他形式的 “Sarafloxacin hydrochloride”:
Sarafloxacin-d8 Hydrochloride
Sarafloxacin hydrochloride (Standard)
Sarafloxacin

Sarafloxacin hydrochloride

一键复制产品信息
Rating icon 很棒

纯度: 97.44%

货号 T1107 别名 盐酸沙拉沙星, Sarafloxacin HCl, A-56620 HCl, A-56620 (hydrochloride)Cas号 91296-87-6

Sarafloxacin hydrochloride (A-56620 (hydrochloride)) 是一种抗菌化合物。

规格价格库存数量
100 mg
¥ 135
现货
500 mg
¥ 297
现货
1 g
¥ 433
现货
1 mL x 10 mM (in DMSO)
¥ 281
现货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
选择批次:
纯度: 97.44%
联系我们 获取更多批次信息
资源下载:
COA HNMR LCMS产品操作手册

产品介绍

Sarafloxacin hydrochloride AI Summary
Sarafloxacin hydrochloride exhibits potent in vitro antibacterial activity against a wide range of bacteria, including Staphylococcus aureus, Staphylococcus epidermis, Streptococcus faecium, Streptococcus pyogenes, Escherichia coli, Enterobacter aerogenes, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter, with minimal inhibitory concentrations (MIC) ranging from 0.02 to 1.56 µg/mL. The compound also demonstrates significant in vivo antibacterial efficacy against systemic infections by Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa in mice, with effective dose (ED50) values ranging from 0.6 to 21.4 mg/kg when administered subcutaneously or orally. Additionally, Sarafloxacin hydrochloride shows inhibition against various enzyme and receptor targets, including Lamin A splicing, HSD17B4, JMJD2E, ALDH1A1, HPGD, and the vitamin D receptor (VDR), with potencies ranging from 2238.7 nM to 100000.0 nM. It also acts as a delayed death inhibitor of the malarial parasite plastid and inhibits human tyrosyl-DNA phosphodiesterase 1 (TDP1) under varying conditions, with potencies between 14581.0 nM and 23715.0 nM. Furthermore, Sarafloxacin hydrochloride exhibits antiviral properties, including inhibition of SARS-CoV-2 induced cytotoxicity in Caco-2 and VERO-6 cells at 10 µM concentration after 48 hours, as well as protease inhibition against the SARS-CoV-2 3CL-Pro protease, although these activities show variable inhibition percentages. The compound also demonstrates the ability to inhibit sodium fluorescein uptake in OATP1B1- and OATP1B3-transfected CHO cells with inhibition rates of 109.55% and 115.57%, respectively, at an equimolar concentration of 10 µM..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
Sarafloxacin hydrochloride (A-56620 (hydrochloride)), a quinolone antibiotic drug, is a hydrochloride salt form of sarafloxacin.
别名盐酸沙拉沙星, Sarafloxacin HCl, A-56620 HCl, A-56620 (hydrochloride)
化学信息
分子量421.83
分子式C20H18ClF2N3O3
CAS No.91296-87-6
SmilesCl.OC(=O)C1=CN(C2=CC=C(F)C=C2)C2=CC(N3CCNCC3)=C(F)C=C2C1=O
密度no data available
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
溶解度信息
DMSO: 5.5 mg/mL (13.04 mM), Sonication is recommended.
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM2.3706 mL11.8531 mL23.7062 mL118.5312 mL
5 mM0.4741 mL2.3706 mL4.7412 mL23.7062 mL
10 mM0.2371 mL1.1853 mL2.3706 mL11.8531 mL

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL， 一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O， 那么您的工作液浓度为2 mg/mL。
母液配置方法：2 mg 药物溶于 100 μL DMSO （ 母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。
体内配方的制备方法： 取 100 μL DMSO 母液， 添加 400 μL PEG300 混匀澄清， 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD， 玉米油等， 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成，不同的产品配方组成不同，如有配方需求，可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

关键词

Sarafloxacin hydrochlorideSarafloxacinInhibitorinhibitBacterialAntibioticA-56620A56620A 56620
Related Tags: buy Sarafloxacin hydrochloride | purchase Sarafloxacin hydrochloride | Sarafloxacin hydrochloride cost | order Sarafloxacin hydrochloride | Sarafloxacin hydrochloride chemical structure | Sarafloxacin hydrochloride formula | Sarafloxacin hydrochloride molecular weight