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Anti-Cip4 Antibody (7W163)

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货号 TMAB-04360

Anti-Cip4 Antibody (7W163) 是一种 Rabbit 抗体,靶向 Cip4。Anti-Cip4 Antibody (7W163) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Cip4 Antibody (7W163)

Anti-Cip4 Antibody (7W163)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04360

Anti-Cip4 Antibody (7W163) 是一种 Rabbit 抗体,靶向 Cip4。Anti-Cip4 Antibody (7W163) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-Cip4 Antibody (7W163) is a Rabbit antibody targeting Cip4. Anti-Cip4 Antibody (7W163) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
7W163
反应种属
Human,Mouse
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Golgi apparatus. Cell membrane. Cell projection, phagocytic cup. Note=Translocates to the plasma membrane in response to insulin stimulation, and this may require active RHOQ (By similarity). Localizes to cortical regions coincident with F-actin, to lysosomes and to sites of phagocytosis in macrophages. Also localizes to the Golgi, and this requires AKAP9. Isoform 5: Cytoplasm, perinuclear region.
组织特异性Expressed in brain, colon, heart, kidney, liver, lung, megakaryocyte, ovary, pancreas, peripheral blood lymphocytes, placenta, prostate, skeletal muscle, small intestine, spleen, testis, thymus and trachea.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity).Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules.
抗原信息
免疫原
A synthesized peptide: human TRIP10
抗原种属
Human
基因名称
TRIP10
基因ID
蛋白名称
Cdc42-interacting protein 4
Uniprot ID
功能
Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
化学信息
分子量Theoretical: 68 kDa. Actual: 75 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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