规格

价格

库存

数量

1 mg

¥ 783

现货

5 mg

¥ 1,990

现货

10 mg

¥ 3,230

现货

25 mg

¥ 5,190

现货

生物活性

产品描述

LysoTracker Yellow HCK 123 is a highly selective fluorescent probe designed for labeling acidic organelles in live cells, particularly lysosomes. The probe accumulates in acidic compartments via its weak base moiety. In plant sciences, it has been discovered to specifically label silica-deposition vesicles (SDVs) in diatoms, serving as a vital tool for studying biosilicification. In pharmacological research, it is frequently utilized to track the intracellular localization of drug delivery systems (e.g., polymeric micelles) to verify endocytosis and trafficking pathways through colocalization analysis.

体外活性

在细胞实验中，LysoTracker Yellow HCK 123 的典型工作浓度为 0.1-50 µM。将细胞（如在 8 孔培养板中）在 37 °C、5% CO2 条件下孵育 30 分钟，经 PBS 洗涤后使用共聚焦激光扫描显微镜 (CLSM) 进行观察，可有效实现酸性细胞器可视化并追踪细胞内吞途径 [1][2]。

化学信息

分子量	364.4
分子式	C₁₆H₂₄N₆O₄
CAS No.	1064123-31-4
Smiles	O=C(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C21)NCCN(C)C

储存&溶解度

存储

store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice.

溶解度信息

DMSO: 50 mg/mL (137.21 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7442 mL	13.7212 mL	27.4424 mL	137.2119 mL
5 mM	0.5488 mL	2.7442 mL	5.4885 mL	27.4424 mL
10 mM	0.2744 mL	1.3721 mL	2.7442 mL	13.7212 mL
20 mM	0.1372 mL	0.6861 mL	1.3721 mL	6.8606 mL
50 mM	0.0549 mL	0.2744 mL	0.5488 mL	2.7442 mL
100 mM	0.0274 mL	0.1372 mL	0.2744 mL	1.3721 mL

LysoTracker Yellow HCK 123

LysoTracker Yellow HCK 123

产品介绍

计算器

体内实验配液计算器

剂量转换

引用文献