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SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPY-06226

Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as an estrogen-induced gene in a breast cancer cell line. Generally, elevated SLC39A6 expression is reportedly related to cancer progression in other various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers.

SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)

产品编号 TMPY-06226

规格	价格	库存	数量
100 μg	¥ 5,100	5日内发货
1 mg	¥ 33,200	5日内发货

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产品信息

生物活性	Immobilized Cynomolgus SLC39A6/LIV-1 His at 2 μg/mL (100 μL/well) can bind Rabbit Anti-SLC39A6/LIV-1 Antibody, the EC50 of Rabbit Anti-SLC39A6/LIV-1 Antibody is 15-100 ng/mL.
产品描述	Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as an estrogen-induced gene in a breast cancer cell line. Generally, elevated SLC39A6 expression is reportedly related to cancer progression in other various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers.
种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	A0A2K5WH46-1
别名	solute carrier family 39 member 6
蛋白构建	A DNA sequence encoding the cynomolgus SLC39A6 (A0A2K5WH46-1) (Met1-Gln308) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Leu 21
蛋白纯度	> 95 % as determined by SDS-PAGE.
分子量	34 kDa (predicted)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM MES, 150 mM NaCl, 10% glycerol, 0.02% Tween 80, pH 6. 0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like protein zinc transporters (LZTs). It is involved in maintaining the intracellular homeostasis of zinc, an ion that is essential in the control of cellular growth and differentiation. SLC39A6 plays a critical role in maintaining zinc homeostasis, and was originally identified as an estrogen-induced gene in a breast cancer cell line. Generally, elevated SLC39A6 expression is reportedly related to cancer progression in other various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers.