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Anti-ROCK1 Antibody (4X563) 是一种 Rabbit 抗体,靶向 ROCK1。Anti-ROCK1 Antibody (4X563) 可用于 WB,ICC/IF,IHC,IP,FCM。
Anti-ROCK1 Antibody (4X563) 是一种 Rabbit 抗体,靶向 ROCK1。Anti-ROCK1 Antibody (4X563) 可用于 WB,ICC/IF,IHC,IP,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-ROCK1 Antibody (4X563) is a Rabbit antibody targeting ROCK1. Anti-ROCK1 Antibody (4X563) can be used in WB,ICC/IF,IHC,IP,FCM. |
别名 | ROCK 1, Rho associated protein kinase 1, Rho associated coiled coil containing protein kinase 1, Renal carcinoma antigen NY REN 35, p160ROCK, p160 ROCK1 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of ROCK1 on different lysates using anti-ROCK1 antibody at 1/1,000 dilution. Positive control: Lane 1: A431, Lane 2: NIH/3T3. 2. Immunohistochemical analysis of paraffin-embedded mouse thyroid tissue using anti-ROCK1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-ROCK1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human thyroid tissue using anti-ROCK1 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Rho, the Ras-related small GTPase, is responsible for the regulation of Actin-based cytoskeletal structures including stress fibers, focal adhesions and the contractile ring apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been described, including rhophilin, Rhotekin, citron and the serine/threonine kinase, protein kinase N. Two additional Rho-activated serine/threonine kinases have been described, designated Rock-1 and Rock-2 (also referred to as Roka, for Rho-associated coil-containing protein kinase). Rock-1 and Rock-2 share a structural similarity with myotonic dystrophy kinase. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 158 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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