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Anti-VEGFA Antibody (1L207)
还可以产品编号 TMAY-00342
Anti-VEGFA Antibody (1L207) 是一种 Mouse 抗体，靶向 VEGFA。Anti-VEGFA Antibody (1L207) 可用于 IHC-P。
Anti-VEGFA Antibody (1L207)
Anti-VEGFA Antibody (1L207)
还可以产品编号 TMAY-00342
Anti-VEGFA Antibody (1L207) 是一种 Mouse 抗体，靶向 VEGFA。Anti-VEGFA Antibody (1L207) 可用于 IHC-P。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-VEGFA Antibody (1L207) is a Mouse antibody targeting VEGFA. Anti-VEGFA Antibody (1L207) can be used in IHC-P. |
| Ig Type | Monoclonal Mouse IgG3 |
| 克隆号 | 1L207 |
| 交叉反应 | Human, Cynomolgus |
| 验证活性 | 1. Immunochemical staining VEGFA in human liver with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 2. Immunochemical staining VEGFA in human kidney with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). 3. Immunochemical staining VEGFA in cynomolgus heart with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:50-1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the C-terminus of the Human VEGF/VEGFA. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family and often exists as a disulfide-linked homodimer. VEGF-A protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, inhibiting apoptosis and tumor growth. VEGF-A protein is also a vasodilator that increases microvascular permeability, thus it was originally referred to as vascular permeability factor.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the C-terminus of the Human VEGF/VEGFA |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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