您的购物车当前为空
Anti-ACVR2B Antibody是一种针对人激活素受体IIB (ACVR2B)的高特异性单克隆抗体。Anti-ACVR2B Antibody通过结合ACVR2B的胞外域,特异性阻断激活素(Activin)和肌肉抑制素(Myostatin)介导的信号传导,从而抑制下游Smad2/3的磷酸化。Anti-ACVR2B Antibody作为调节肌肉量和代谢稳态的关键工具,被广泛用于研究肌肉萎缩、骨质疏松及癌症相关的恶病质。
别名 抗ACVR2B抗体
Anti-ACVR2B Antibody是一种针对人激活素受体IIB (ACVR2B)的高特异性单克隆抗体。Anti-ACVR2B Antibody通过结合ACVR2B的胞外域,特异性阻断激活素(Activin)和肌肉抑制素(Myostatin)介导的信号传导,从而抑制下游Smad2/3的磷酸化。Anti-ACVR2B Antibody作为调节肌肉量和代谢稳态的关键工具,被广泛用于研究肌肉萎缩、骨质疏松及癌症相关的恶病质。


TargetMol的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
| 产品描述 | Anti-ACVR2B Antibody is a highly specific monoclonal antibody targeting the human activin receptor type IIB (ACVR2B). The compound binds to the extracellular domain of ACVR2B to effectively block signaling mediated by ligands such as activin and myostatin, thereby inhibiting downstream Smad2/3 phosphorylation. In experimental research, it serves as a critical tool for modulating muscle mass and metabolic homeostasis to investigate muscle atrophy, osteoporosis, and cancer-associated cachexia. |
| 别名 | 抗ACVR2B抗体 |
| 反应种属 | Human |
| 应用 | ELISAFACSFunctional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | IgG1 |
| 偶联 | Unconjugated |
| Uniprot ID | |
| 靶点 | ACVR2B |
| 存储 | Store at -20°C Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准 |
对于不同动物的给药剂量换算,您也可以参考 更多