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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CCR3 Polyclonal Antibody 2

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货号 TMAB-03801

Anti-CCR3 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CCR3。Anti-CCR3 Polyclonal Antibody 2 可用于 WB。

Anti-CCR3 Polyclonal Antibody 2

Anti-CCR3 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-03801

Anti-CCR3 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CCR3。Anti-CCR3 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-CCR3 Polyclonal Antibody 2 is a Rabbit antibody targeting CCR3. Anti-CCR3 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein.
组织特异性In eosinophils as well as trace amounts in neutrophils and monocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3(CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants encoding the same protein have been described.
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse CCR3
抗原种属
Mouse
基因名称
CCR3
基因ID
12771
蛋白名称
C-C chemokine receptor type 3
Uniprot ID
P51678
功能
Receptor for a C-C type chemokine. Binds to eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES and MIP-1 delta. Subsequently transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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