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Anti-IGSF8 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IGSF8。Anti-IGSF8 Polyclonal Antibody 可用于 FCM。
Anti-IGSF8 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IGSF8。Anti-IGSF8 Polyclonal Antibody 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-IGSF8 Polyclonal Antibody is a Rabbit antibody targeting IGSF8. Anti-IGSF8 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Pig,Cow,Horse) |
| 应用 | FCM |
| 推荐剂量 | FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Single-pass membrane protein. |
| 组织特异性 | Expressed in lymphocytes as well as in many tissues with higher expression in brain. Detected in all regions of the brain with weak expression in the pituitary. Expressed selectively by neurons but not by glial cells. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | IGSF8 is a 65kDa single-pass membrane protein that may play a key role in many of the functions attributed to CD81 and CD9, like Hepatitis C infection and oocyte fertilization. It is also believed that this protein acts as a negative regulator of cell motility (e.g. T-cell mobility, prostate cancer cell migration) and is involved in the regulation of neurite outgrowth and maintenance of the neural network in the brain. |
| 免疫原 | KLH conjugated synthetic peptide: mouse IGSF8 |
| 抗原种属 | Mouse |
| 基因名称 | IGSF8 |
| 基因ID | |
| 蛋白名称 | Immunoglobulin superfamily member 8 |
| Uniprot ID | |
| 功能 | May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. |
| 分子量 | Theoretical: 62 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |