规格

价格

库存

数量

2 mg

¥ 720

5日内发货

生物活性

产品描述	Cimetidine sulfoxide (Cimetidine sulphoxide) is a metabolite of Cimetidine, functioning as a histamine H2-receptor antagonist with potential applications in treating peptic ulcer disease and upper gastrointestinal hemorrhage[1].
体外活性	Active transport of Cimetidine across the rat small intestine is observable at lower substrate concentrations (40 and 200 μM), but is masked by passive transfer at higher concentrations (400 μM). Cimetidine sulfoxide is detected after some incubations[2].
体内活性	The enantiomeric composition of Cimetidine sulfoxide is also determined in rat urine (24 h) following the administration of Cimetidine (30 mg/kg; po) to male Wistar rats. The enantiomeric ratio in this case is found to be (+/-) 57:43[3].
别名	西咪替丁亚砜

化学信息

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 83.33 mg/mL (310.54 mM), Sonication and heating to 60℃ are recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (12.3 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

Cimetidine sulfoxide