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Anti-FSTL3 Antibody (4S786) 是一种 Rabbit 抗体,靶向 FSTL3。Anti-FSTL3 Antibody (4S786) 可用于 IHC-P,IHC-Fr,IF,ICC/IF。
Anti-FSTL3 Antibody (4S786) 是一种 Rabbit 抗体,靶向 FSTL3。Anti-FSTL3 Antibody (4S786) 可用于 IHC-P,IHC-Fr,IF,ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 785 | 5日内发货 | |
| 50 μL | ¥ 1,395 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-FSTL3 Antibody (4S786) is a Rabbit antibody targeting FSTL3. Anti-FSTL3 Antibody (4S786) can be used in IHC-P,IHC-Fr,IF,ICC/IF. |
| Ig Type | IgG |
| 克隆号 | 4S786 |
| 反应种属 | Human |
| 应用 | IHC-PIHC-FrIFICC/IF |
| 推荐剂量 | IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; ICC/IF: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted and Nucleus. Although alternative initiation has been demonstrated and resulted in different localization, the major source of nuclear FSTL3 appears not to depend on translation initiation at Met-27 according to. |
| 组织特异性 | Expressed in a wide range of tissues. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.22μm filtered solution in 20mM hepes7.4, 150mm NaCl, 50% glycerin,0.03% proclin. |
| 浓度 | 1mg/ml |
| 研究背景 | FLRG (follistatin-related gene, follistatin-like-3 or FSTL3) is a member of the follistatin-module protein family, which is composed of extracellular matrix-associated glycoproteins thought to act in a paracrine manner to bind morphogens or growth/differen-tiation factors and regulate their activity during development. The FSTL3 protein contains 2 potential N-glycosylation sites and the predicted mass of the unmodified core protein is 27 kDa. FLRG is expressed in a wide range of human and murine adult tissues and its expression seems to be tightly regulated during murine embryogenesis. Immunohistochemistry reveals the presence of FLRG in the basement membrane between the dermis and the epidermis and around blood vessels. |
| 免疫原 | KLH conjugated synthetic peptide: human FSTL3 |
| 抗原种属 | Human |
| 基因名称 | FSTL3 |
| 基因ID | |
| 蛋白名称 | Follistatin-related protein 3 |
| Uniprot ID | |
| 功能 | Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10. |
| 分子量 | Theoretical: 28 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |