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Anti-FSTL3 Antibody (4S786)

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货号 TMAB-06192

Anti-FSTL3 Antibody (4S786) 是一种 Rabbit 抗体,靶向 FSTL3。Anti-FSTL3 Antibody (4S786) 可用于 IHC-P,IHC-Fr,IF,ICC/IF。

Anti-FSTL3 Antibody (4S786)

Anti-FSTL3 Antibody (4S786)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06192

Anti-FSTL3 Antibody (4S786) 是一种 Rabbit 抗体,靶向 FSTL3。Anti-FSTL3 Antibody (4S786) 可用于 IHC-P,IHC-Fr,IF,ICC/IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-FSTL3 Antibody (4S786) is a Rabbit antibody targeting FSTL3. Anti-FSTL3 Antibody (4S786) can be used in IHC-P,IHC-Fr,IF,ICC/IF.
Ig Type
IgG
克隆号
4S786
反应种属
Human
应用IHC-PIHC-FrIFICC/IF
推荐剂量
IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted and Nucleus. Although alternative initiation has been demonstrated and resulted in different localization, the major source of nuclear FSTL3 appears not to depend on translation initiation at Met-27 according to.
组织特异性Expressed in a wide range of tissues.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.22μm filtered solution in 20mM hepes7.4, 150mm NaCl, 50% glycerin,0.03% proclin.
浓度1mg/ml
研究背景FLRG (follistatin-related gene, follistatin-like-3 or FSTL3) is a member of the follistatin-module protein family, which is composed of extracellular matrix-associated glycoproteins thought to act in a paracrine manner to bind morphogens or growth/differen-tiation factors and regulate their activity during development. The FSTL3 protein contains 2 potential N-glycosylation sites and the predicted mass of the unmodified core protein is 27 kDa. FLRG is expressed in a wide range of human and murine adult tissues and its expression seems to be tightly regulated during murine embryogenesis. Immunohistochemistry reveals the presence of FLRG in the basement membrane between the dermis and the epidermis and around blood vessels.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FSTL3
抗原种属
Human
基因名称
FSTL3
基因ID
蛋白名称
Follistatin-related protein 3
Uniprot ID
功能
Isoform 1 or the secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiationc. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. Isoform 2 or the nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.
化学信息
分子量Theoretical: 28 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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