Name: IL-23R Protein, Cynomolgus, Recombinant (His)
Brand: TargetMol
SKU: TMPK-00652
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 358

6-8日内发货

10 μg

¥ 573

6-8日内发货

20 μg

¥ 938

5日内发货

50 μg

¥ 1,830

5日内发货

100 μg

¥ 3,100

5日内发货

200 μg

¥ 5,620

5日内发货

500 μg

¥ 12,400

5日内发货

生物活性

产品描述	IL-23R Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.03 kDa and the accession number is G7NWY5.
生物活性	1. Immobilized Cynomolgus IL-23R, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-23 alpha&IL-12 beta, His Tag with the EC50 of 0.25μg/ml determined by ELISA (QC Test). 2. Cynomolgus IL-23R, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-23 alpha&Mouse IL-12 beta, His Tag with an affinity constant of 3.90 nM as determined in SPR assay.
研究背景	Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 R beta 1) and the IL-23-specific receptor subunit (IL-23 R).This receptor associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade.
种属	Cynomolgus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	G7NWY5
蛋白构建	Gly24-Asp353
蛋白纯度	> 95% as determined by Tris-Bis PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	IL-23 receptor, IL-23 R, IBD17
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	39.03 kDa (predicted). Due to glycosylation, the protein migrates to 60-80 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

IL-23R Protein, Cynomolgus, Recombinant (His)

IL-23R Protein, Cynomolgus, Recombinant (His)

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