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CRADD Protein, Human, Recombinant

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货号 TMPJ-01059

别名 RIP-Associated Protein with A Death Domain, RAIDD, Death Domain-Containing Protein CRADD, CRADD, Caspase and RIP Adapter with Death Domain

Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.

CRADD Protein, Human, Recombinant
其他形式的 “CRADD Protein, Human, Recombinant”:
RAIDD Protein, Human, Recombinant (His)TMPY-02213
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CRADD Protein, Human, Recombinant

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SPR兼容缓冲液
货号 TMPJ-01059 别名 RIP-Associated Protein with A Death Domain, RAIDD, Death Domain-Containing Protein CRADD, CRADD, Caspase and RIP Adapter with Death Domain

Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.

规格价格库存数量
5 μg
¥ 693
6-8日内发货
10 μg
¥ 1,170
6-8日内发货
20 μg
¥ 1,860
5日内发货
50 μg
¥ 3,470
5日内发货
100 μg
¥ 5,180
5日内发货
200 μg
¥ 7,730
5日内发货
500 μg
¥ 13,200
5日内发货
1 mg
¥ 18,900
5日内发货
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产品介绍

生物活性
产品描述
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.
种属
Human
表达系统
E. coli
标签Tag Free
蛋白编号P78560
氨基酸序列Met1-Glu199
蛋白构建Met1-Glu199
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名RIP-Associated Protein with A Death Domain, RAIDD, Death Domain-Containing Protein CRADD, CRADD, Caspase and RIP Adapter with Death Domain
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量21 KDa (reducing condition)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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  • 重组蛋白稀释 计算器
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剂量转换

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技术支持

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