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Anti-NHERF1 Antibody (1A168)
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产品编号 TMAC-01219
别名 Solute carrier family 9 isoform A3 regulatory factor 1, Sodium-hydrogen exchanger regulatory factor 1, SLC9A3R1, Regulatory cofactor of Na(+)/H(+) exchanger, NHERF-1, NHERF1, NHERF, Na(+)/H(+) exchange regulatory cofactor NHE-RF1, Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50)
Anti-NHERF1 Antibody (1A168) 是一种 Rabbit 抗体，靶向 NHERF1。Anti-NHERF1 Antibody (1A168) 可用于 WB,IHC。
Anti-NHERF1 Antibody (1A168)
Anti-NHERF1 Antibody (1A168)
还可以产品编号 TMAC-01219 别名 Solute carrier family 9 isoform A3 regulatory factor 1, Sodium-hydrogen exchanger regulatory factor 1, SLC9A3R1, Regulatory cofactor of Na(+)/H(+) exchanger, NHERF-1, NHERF1, NHERF, Na(+)/H(+) exchange regulatory cofactor NHE-RF1, Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50)
Anti-NHERF1 Antibody (1A168) 是一种 Rabbit 抗体，靶向 NHERF1。Anti-NHERF1 Antibody (1A168) 可用于 WB,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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| 产品描述 | Anti-NHERF1 Antibody (1A168) is a Rabbit antibody targeting NHERF1. Anti-NHERF1 Antibody (1A168) can be used in WB,IHC. |
| 别名 | Solute carrier family 9 isoform A3 regulatory factor 1, Sodium-hydrogen exchanger regulatory factor 1, SLC9A3R1, Regulatory cofactor of Na(+)/H(+) exchanger, NHERF-1, NHERF1, NHERF, Na(+)/H(+) exchange regulatory cofactor NHE-RF1, Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) |
| Ig Type | IgG |
| 克隆号 | 1A168 |
| 交叉反应 | Human,Rat |
| 验证活性 | 1. Western blot analysis of EBP50 on MCF-7 cells lysates using anti-EBP50 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat kidney tissue using anti-EBP50 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-EBP50 antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The Na+/H+ exchange protein (NHE3) functions in transepithelial Na+ absorption and is primarily expressed in the intestinal and renal brush border membrane. NHE3 regulatory factor 1 (NHERF-1) interacts with NHE3 through two PDZ (for PSD-95, Discs-large and ZO-1 homology) domains, which are protein-protein interaction modules that associate with specific carboxy-terminal motifs on target proteins. Also known as EBP50, NHERF-1 facilitates cAMP inhibition of NHE3 to decrease Na+ adsorption. NHERF-1 functions as a scaffold for an essential multiprotein complex of Ezrin and NHE3 for cAMP-mediated phosphorylation and consequent inhibition of NHE3. The amino-terminal PDZ domain regulates the dimerization of NHERF-1 in vivo. G protein-coupled receptor kinase 6A phosphorylates NHERF-1 at Ser 289 via a PDZ domain-mediated interaction. NHERF-2, also known as E3KARP, is a ubiquitously expressed protein which also functions in NHE2 regulation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 50 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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