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顶部生物活性储存和溶解信息计算器

Anti-Vitamin D Receptor/VDR Antibody (5D259)

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产品编号 TMAC-04265

别名 vitamin D (1,25- dihydroxyvitamin D3) receptor, PPP1R163, NR1I1

Anti-Vitamin D Receptor/VDR Antibody (5D259) 是一种 Rabbit 抗体，靶向 Vitamin D Receptor/VDR。Anti-Vitamin D Receptor/VDR Antibody (5D259) 可用于 FCM,IHC,WB。

Anti-Vitamin D Receptor/VDR Antibody (5D259)

Anti-Vitamin D Receptor/VDR Antibody (5D259)

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产品编号 TMAC-04265 别名 vitamin D (1,25- dihydroxyvitamin D3) receptor, PPP1R163, NR1I1

Anti-Vitamin D Receptor/VDR Antibody (5D259) 是一种 Rabbit 抗体，靶向 Vitamin D Receptor/VDR。Anti-Vitamin D Receptor/VDR Antibody (5D259) 可用于 FCM,IHC,WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Vitamin D Receptor/VDR Antibody (5D259) is a Rabbit antibody targeting Vitamin D Receptor/VDR. Anti-Vitamin D Receptor/VDR Antibody (5D259) can be used in FCM,IHC,WB.
别名vitamin D (1,25- dihydroxyvitamin D3) receptor, PPP1R163, NR1I1
Ig Type
IgG
克隆号
5D259
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti- Vitamin D Receptor antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded mouse colon tissue using anti- Vitamin D Receptor antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti- Vitamin D Receptor antibody. Counter stained with hematoxylin.
4. Flow cytometric analysis of Hela cells with Vitamin D Receptor antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用FCMIHCWB
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景he active metabolite of vitamin D modulates the expression of a wide variety of genes in a developmentally specific manner. This secosteroid hormone can up- or downregulate the expression of genes involved in a diverse array of responses such as proliferation, differentiation and calcium homeostasis. 1,25-(OH)2-vitamin D3 exerts its effects through interaction with the vitamin D receptor (VDR), a member of the superfamily of hormone-activated nuclear receptors. In its ligand-bound state, the VDR forms heterodimers with the 9-cis retinoic acid receptor, RXR, and affects gene expression by binding specific DNA sequences known as hormone response elements, or HREs. In addition to regulating the above-mentioned cellular responses, 1,25-(OH)2-vitamin D3 exhibits antiproliferative properties in osteosarcoma, melanoma, colon carcinoma and breast carcinoma cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P11473
化学信息
分子量Theoretical: 48 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

PPP1R-163PPP1R 163

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