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顶部生物活性储存和溶解信息计算器

Anti-Phospho-BACE1 (Ser498) Polyclonal Antibody 2

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产品编号 TMAB-10365

Anti-Phospho-BACE1 (Ser498) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-BACE1 (Ser498)。Anti-Phospho-BACE1 (Ser498) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-BACE1 (Ser498) Polyclonal Antibody 2

Anti-Phospho-BACE1 (Ser498) Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10365

Anti-Phospho-BACE1 (Ser498) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-BACE1 (Ser498)。Anti-Phospho-BACE1 (Ser498) Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-BACE1 (Ser498) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-BACE1 (Ser498). Anti-Phospho-BACE1 (Ser498) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性Expressed at high levels in the brain and pancreas. In the brain, expression is highest in the substantia nigra, locus coruleus and medulla oblongata.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景bs-0164P is one synthetic peptide derived from human BACE1. Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein(APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human BACE1 around the phosphorylation site of Ser498
抗原种属
Human
基因名称
BACE1
基因ID
23621
蛋白名称
beta-secretase 1
Uniprot ID
P56817
功能
Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
化学信息
分子量Theoretical: 51 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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