Name: Anti-IGF-2 Antibody (DX-2647)
Brand: TargetMol
SKU: T9901A-1445
Rating: 4.5 (1 reviews)

生物活性

产品描述	Anti-IGF-2 Antibody (DX-2647) is a potent humanized monoclonal antibody targeting human insulin-like growth factor 2 (IGF-2), acting by disrupting its interaction with receptors such as IGF-1R and IR-A. The compound is an essential tool for investigating the role of the IGF axis in tumor proliferation and placental development, aiming to reverse abnormal tumor growth by inhibiting the IGF signaling axis.
体外活性	在人肝细胞癌细胞系中，Anti-IGF-2 Antibody (DX-2647) 阻断了 IGF-2 结合并抑制了细胞增殖和生存信号 [1]。
体内活性	在人 HCC 异种移植模型中，通过全身给药方式给予 Anti-IGF-2 Antibody (DX-2647) 显著抑制了肿瘤生长 [1]。
别名	抗IGF-2 抗体(DX-2647), DX-2647
克隆号	DX-2647
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型

IgG1

偶联与修饰

偶联	Unconjugated

抗原信息

Uniprot ID	P01344
靶点	IGF-2

储存&溶解度

存储

Anti-IGF-2 Antibody (DX-2647)