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Anti-HLA-DPB1 Antibody (7X876) 是一种 Rabbit 抗体,靶向 HLA-DPB1。Anti-HLA-DPB1 Antibody (7X876) 可用于 WB,IP,ICC/IF,IHC。
Anti-HLA-DPB1 Antibody (7X876) 是一种 Rabbit 抗体,靶向 HLA-DPB1。Anti-HLA-DPB1 Antibody (7X876) 可用于 WB,IP,ICC/IF,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-HLA-DPB1 Antibody (7X876) is a Rabbit antibody targeting HLA-DPB1. Anti-HLA-DPB1 Antibody (7X876) can be used in WB,IP,ICC/IF,IHC. |
别名 | MHC class II antigen DPB1, HLA-DPB1, HLA-DP1B, HLA class II histocompatibility antigen, DP(W4) beta chain, HLA class II histocompatibility antigen, DP beta 1 chain, DP beta 1 chain |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti- MHC Class II antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti- MHC Class II antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-100; IP: 1:10-50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Major histocompatibility complex (MHC) molecules, also designated human leukocyte antigen (HLA) molecules, are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an α or heavy chain and β-2-Microglobulin, a non-covalently associated protein. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically eight to ten residues in length and are stabilized in a peptide binding groove. MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an α and β chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumu-lating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 29 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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