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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SOX9 Antibody (4M70)

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货号 TMAB-13071

Anti-SOX9 Antibody (4M70) 是一种 Rabbit 抗体，靶向 SOX9。Anti-SOX9 Antibody (4M70) 可用于 WB,IHC-P,IF,IHC-Fr。

Anti-SOX9 Antibody (4M70)

Anti-SOX9 Antibody (4M70)

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Rating icon 还可以
货号 TMAB-13071

Anti-SOX9 Antibody (4M70) 是一种 Rabbit 抗体，靶向 SOX9。Anti-SOX9 Antibody (4M70) 可用于 WB,IHC-P,IF,IHC-Fr。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-SOX9 Antibody (4M70) is a Rabbit antibody targeting SOX9. Anti-SOX9 Antibody (4M70) can be used in WB,IHC-P,IF,IHC-Fr.
Ig Type
IgG
克隆号
4M70
反应种属
Human,Mouse,Rat
应用WBIHC-PIFIHC-Fr
推荐剂量
WB: 1:1000-5000; IHC-P: 1:200-1000; IF: 1:200-1000; IHC-Fr: 1:200-1000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm (By similarity). Note=Restricted to the nucleus of Sertoli-like cells in the testis, but localizes to the cytoplasm of previtellogenic oocytes in the ovary before being translocated into the nucleus of vitellogenic oocytes (By similarity).
组织特异性From mid-gastrula (stage 10.5-11), expressed in a ring around the blastopore, with expression decreasing toward the dorsal side. At stage 12, expression around the blastopore decreases and begins to increase lateral to the neural plate in the presumptive neural crest, where expression dramatically increases around stage 14. Also expressed in the otic placode as early as stage 13/14. By the tailbud stage expression is restricted to the otic cup and then throughout the otic vesicle, with more intense staining at the dorsal-most region, the prospective region of the semicircular canals and endolymphatic duct. At the early tailbud stage (stage 23), expressed in migrating cranial neural crest cells and in the trunk neural crest. Also expressed in the genital ridges, developing eye, nasal placode and prospective pineal gland. Around stage 25, expression is down-regulated in the trunk neural crest but persists in the migrating cranial crest cells as they populate the pharyngeal arches, otic placode, developing eye, genital ridges and notochord. By stage 31, expression remains strong in the pharyngeal arches. Also expressed in the pancreas; first expressed at stage 25 in the pancreatic anlagen, dorsally in diverticulum. As development proceeds, expression continues in pancreatic tissue, being restricted to ventral and dorsal pancreatic buds.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景May be involved in chondrogenesis (cartilage development) during bone formation. Unlikely to play a role in sex determination but may function during testicular and ovarian differentiation (By similarity). Transcriptional activator. Acts early in neural crest formation, functioning redundantly with the other group E Sox factors sox8 and sox10 to induce neural crest progenitors. Induces sox10 expression downstream of wnt-signaling. Principally involved in development of the cranial neural crest, which is fated to form skeletal elements. Also required for otic placode specification during inner ear development.
抗原信息
免疫原
A synthesized peptide: human SOX9
抗原种属
Human
基因名称
SOX9
基因ID
6662
蛋白名称
Transcription factor SOX-9
功能
Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.
化学信息
分子量Theoretical: 56 kDa. Actual: 70 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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