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Anti-IL-1R2 Antibody (9R858)

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Anti-IL-1R2 Antibody (9R858)
产品编号 TMAY-03766
别名 interleukin 1 receptor, type II

Anti-IL-1R2 Antibody (9R858) 是一种 Mouse 抗体,靶向 IL-1R2。Anti-IL-1R2 Antibody (9R858) 可用于 ELISA,ELISA(Det)。

Anti-IL-1R2 Antibody (9R858)
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Anti-IL-1R2 Antibody (9R858)

Rating icon 还可以
Anti-IL-1R2 Antibody (9R858)
产品编号 TMAY-03766 别名 interleukin 1 receptor, type II

Anti-IL-1R2 Antibody (9R858) 是一种 Mouse 抗体,靶向 IL-1R2。Anti-IL-1R2 Antibody (9R858) 可用于 ELISA,ELISA(Det)。

规格价格库存数量
20 μL
¥ 585
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100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-1R2 Antibody (9R858) is a Mouse antibody targeting IL-1R2. Anti-IL-1R2 Antibody (9R858) can be used in ELISA,ELISA(Det).
别名interleukin 1 receptor, type II
Ig Type
Mouse IgG1
克隆号
9R858
交叉反应
Rat
应用
ELISA,ELISA(Det)
推荐剂量
ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat IL-1R2 / CD121b (TMPY-02825; P43303; Met1-Glu355). The IgG fraction of the cell culture supernatant was purified by Protein A affinity.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. The pleiotropic cytokine IL1 is produced to regulate the development and maintenance of the inflammatory responses and binds to specific plasma membrane receptors on cells. Two distinct types of IL1 receptors that can bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R1 contributes to IL-1 signaling, whereas the IL-1R2/CD121b has no signaling property and acts as a decoy for IL-1. IL-1R2/CD121b structurally consisting of a ligand-binding portion comprised of three Ig-like domains, a single transmembrane region, and a short cytoplasmic domain is expressed in a variety of cell types including B lymphocytes, neutrophils, monocytes, large granular leukocytes, and endothelial cells. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
HRP
可提供抗体种类
2
抗原信息
免疫原
Recombinant Protein: Rat IL-1R2 / CD121b protein (TMPY-02825)
抗原种属
Rat
研究领域
Neuroinflammation
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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