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Anti-OPG Antibody (1I569)

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货号 TMAB-09782

Anti-OPG Antibody (1I569) 是一种 Rabbit 抗体,靶向 OPG。Anti-OPG Antibody (1I569) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-OPG Antibody (1I569)

Anti-OPG Antibody (1I569)

一键复制产品信息
Rating icon 还可以
货号 TMAB-09782

Anti-OPG Antibody (1I569) 是一种 Rabbit 抗体,靶向 OPG。Anti-OPG Antibody (1I569) 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍


生物活性
产品描述
Anti-OPG Antibody (1I569) is a Rabbit antibody targeting OPG. Anti-OPG Antibody (1I569) can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
1I569
反应种属
Human
应用IHC-PIHC-FrICC/IFIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Highly expressed in adult lung, heart, kidney, liver, spleen, thymus, prostate, ovary, small intestine, thyroid, lymph node, trachea, adrenal gland, testis, and bone marrow. Detected at very low levels in brain, placenta and skeletal muscle. Highly expressed in fetal kidney, liver and lung.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Acts as a decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B.
抗原信息
免疫原
A synthesized peptide: human TNFRSF11B
抗原种属
Human
基因名称
TNFRSF11B
基因ID
蛋白名称
Tumor necrosis factor receptor superfamily member 11B
Uniprot ID
功能
Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
化学信息
分子量Theoretical: 46 kDa. Actual: 46 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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