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Anti-GPRC5D Antibody (2N672)

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产品编号 TMAY-02845
别名 GPRC5D

Anti-GPRC5D Antibody (2N672) 是一种 Mouse 抗体,靶向 GPRC5D。Anti-GPRC5D Antibody (2N672) 可用于 ELISA,FCM。

Anti-GPRC5D Antibody (2N672)

Anti-GPRC5D Antibody (2N672)

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产品编号 TMAY-02845 别名 GPRC5D

Anti-GPRC5D Antibody (2N672) 是一种 Mouse 抗体,靶向 GPRC5D。Anti-GPRC5D Antibody (2N672) 可用于 ELISA,FCM。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-GPRC5D Antibody (2N672) is a Mouse antibody targeting GPRC5D. Anti-GPRC5D Antibody (2N672) can be used in ELISA,FCM.
别名GPRC5D
Ig Type
Mouse IgG2b
克隆号
2N672
交叉反应
Human
特异性
Human GPRC5D
验证活性
1. Flow cytometric analysis of Human GPRC5D expression on CHO-K1-transfected Cells were stained with purified anti-Human GPRC5D, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
2. Measured by its binding ability in a functional ELISA. Immobilized Human GPRC5D-VLP protein at 5 μg/mL (100 μL/well) can bind GPRC5D Antibody, Mouse MAb, the EC50is 0.5-5 ng/mL. The VLP isotype control Protein is the negative control.
应用ELISAFCM
推荐剂量
ELISA: 1:1000-1:2000; FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GPRC5D. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Orphan G-protein-coupled receptor family C group 5 member D (GPRC5D) has seven transmembrane segments forming the core of the receptor, as well as an intracellular C-tail and an extracellular N-terminal domain. GPRC5D is highly and selectively expressed on the surface of CD138+ multiple myeloma (MM) cells, whereas in normal tissues, a much lower expression is limited to plasma cells and certain hard keratinizing tissues. This makes GPRC5D a promising marker for monitoring tumor load and a target antigen for MM-specific T cell-engaging therapies such as bispecific antibodies and CAR-T cells.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human GPRC5D Protein
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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