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Anti-IL-12RB2 Antibody (9D131)
还可以产品编号 TMAY-03105
Anti-IL-12RB2 Antibody (9D131) 是一种 Rabbit 抗体，靶向 IL-12RB2。Anti-IL-12RB2 Antibody (9D131) 可用于 ELISA。
Anti-IL-12RB2 Antibody (9D131)
Anti-IL-12RB2 Antibody (9D131)
还可以产品编号 TMAY-03105
Anti-IL-12RB2 Antibody (9D131) 是一种 Rabbit 抗体，靶向 IL-12RB2。Anti-IL-12RB2 Antibody (9D131) 可用于 ELISA。
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偶联与修饰
抗原信息
| 产品描述 | Anti-IL-12RB2 Antibody (9D131) is a Rabbit antibody targeting IL-12RB2. Anti-IL-12RB2 Antibody (9D131) can be used in ELISA. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 9D131 |
| 交叉反应 | Mouse |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL12RB2 (rM IL12RB2; TMPY-01767; NP_032380.1; Met1-Asn637). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin-12 receptor subunit beta-2 (IL12RB2), also known as IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, and IL-12RB2, is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. IL12RB2 belongs to the type I cytokine receptor family. The coexpression of IL12RB2 and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of IL12RB2 is up-regulated by IFN gamma in Th1 cells and plays a role in Th1 cell differentiation. The up-regulation of IL12RB2 is found to be associated with some infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. IL12RB2 promotes the proliferation of T-cells as well as NK cells. IL12RB2 induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Mouse IL12RB2 protein (TMPY-01767) |
| 抗原种属 | Mouse |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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