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Anti-IL-12RB2 Antibody (9D131)

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Anti-IL-12RB2 Antibody (9D131)
产品编号 TMAY-03105
别名 interleukin 12 receptor, β2, interleukin 12 receptor, beta 2

Anti-IL-12RB2 Antibody (9D131) 是一种 Rabbit 抗体，靶向 IL-12RB2。Anti-IL-12RB2 Antibody (9D131) 可用于 ELISA。

Anti-IL-12RB2 Antibody (9D131)
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Anti-IL-12RB2 Antibody (9D131)

Rating icon 还可以
Anti-IL-12RB2 Antibody (9D131)
产品编号 TMAY-03105 别名 interleukin 12 receptor, β2, interleukin 12 receptor, beta 2

Anti-IL-12RB2 Antibody (9D131) 是一种 Rabbit 抗体，靶向 IL-12RB2。Anti-IL-12RB2 Antibody (9D131) 可用于 ELISA。

规格价格库存数量
20 μL
¥ 795
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100 μL
¥ 2,289
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-12RB2 Antibody (9D131) is a Rabbit antibody targeting IL-12RB2. Anti-IL-12RB2 Antibody (9D131) can be used in ELISA.
别名interleukin 12 receptor, β2, interleukin 12 receptor, beta 2
Ig Type
Rabbit IgG
克隆号
9D131
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL12RB2 (rM IL12RB2; TMPY-01767; NP_032380.1; Met1-Asn637).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interleukin-12 receptor subunit beta-2 (IL12RB2), also known as IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, and IL-12RB2, is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. IL12RB2 belongs to the type I cytokine receptor family. The coexpression of IL12RB2 and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of IL12RB2 is up-regulated by IFN gamma in Th1 cells and plays a role in Th1 cell differentiation. The up-regulation of IL12RB2 is found to be associated with some infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. IL12RB2 promotes the proliferation of T-cells as well as NK cells. IL12RB2 induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse IL12RB2 protein (TMPY-01767)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

interleukin 12 receptor, β 2interleukin 12 receptor, b 2

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