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Anti-EMP-1 Polyclonal Antibody 2

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货号 TMAB-05557

Anti-EMP-1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 EMP-1。Anti-EMP-1 Polyclonal Antibody 2 可用于 WB。

Anti-EMP-1 Polyclonal Antibody 2

Anti-EMP-1 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-05557

Anti-EMP-1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 EMP-1。Anti-EMP-1 Polyclonal Antibody 2 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
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200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-EMP-1 Polyclonal Antibody 2 is a Rabbit antibody targeting EMP-1. Anti-EMP-1 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi-pass membrane protein.
组织特异性Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer.
抗原信息
免疫原
Recombinant Protein: mouse EMP-1 protein
抗原种属
Mouse
基因名称
Emp1
基因ID
蛋白名称
Epithelial membrane protein 1
化学信息
分子量Theoretical: 17 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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