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Anti-EMP-1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 EMP-1。Anti-EMP-1 Polyclonal Antibody 2 可用于 WB。
Anti-EMP-1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 EMP-1。Anti-EMP-1 Polyclonal Antibody 2 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-EMP-1 Polyclonal Antibody 2 is a Rabbit antibody targeting EMP-1. Anti-EMP-1 Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Rat) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Most prominently found in the gastrointestinal tract, skin, lung, and brain but not in liver. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Epithelial membrane protein-1 (EMP-1) is a four pass transmembrane protein consisting of 160 amino acids. It is a member of a small family of epithelial membrane proteins. EMP-1 is very similar in structure to its close relative, Peripheral Myelin Protein 22 (PMP22). It is most predominantly expressed in tissues of the gastrointestinal tract but has also been found to be a junctional protein in the liver expressed along the intercellular border. EMP-1 directly interacts with the C-terminus of the P2X7 receptor and may be involved in membrane blebbing. EMP-1 may also be an important regulator in cell communication, signaling, and adhesion. When EMP-1 is overexpressed, cell proliferation is inhibited, S phase is arrested and G1 phase is prolonged in esophogeal cancer cells. EMP-1 may play a role in tumorigenesis and has been identified as a biomarker for gefitinib treatment resistance for patients with lung cancer. |
| 免疫原 | Recombinant Protein: mouse EMP-1 protein |
| 抗原种属 | Mouse |
| 基因名称 | Emp1 |
| 基因ID | |
| 蛋白名称 | Epithelial membrane protein 1 |
| 分子量 | Theoretical: 17 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |