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Anti-SNAI1 Polyclonal Antibody

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货号 TMAB-01745

别名 Zinc finger protein SNAI1, SNAIL1, SNAI 1, SNAH, SNA, Protein snail homolog 1(Protein sna), Protein snail homolog 1, Protein sna, dJ710H13.1

Anti-SNAI1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SNAI1。Anti-SNAI1 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

Anti-SNAI1 Polyclonal Antibody

Anti-SNAI1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-01745 别名 Zinc finger protein SNAI1, SNAIL1, SNAI 1, SNAH, SNA, Protein snail homolog 1(Protein sna), Protein snail homolog 1, Protein sna, dJ710H13.1

Anti-SNAI1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SNAI1。Anti-SNAI1 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P,WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-SNAI1 Polyclonal Antibody is a Rabbit antibody targeting SNAI1. Anti-SNAI1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
别名Zinc finger protein SNAI1, SNAIL1, SNAI 1, SNAH, SNA, Protein snail homolog 1(Protein sna), Protein snail homolog 1, Protein sna, dJ710H13.1
Ig Type
IgG
反应种属
Human,Mouse,Rat
验证活性
1. 25 μg total protein per Lane of various lysates probed with SNAI1 polyclonal antibody, unconjugated (TMAB-01745) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at RT for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Mouse Placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SNAI1 Polyclonal Antibody, Unconjugated (TMAB-01745) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Rat Placenta; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SNAI1 Polyclonal Antibody, Unconjugated (TMAB-01745) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Rat Colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SNAI1 Polyclonal Antibody, Unconjugated (TMAB-01745) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Human Lung Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SNAI1 Polyclonal Antibody, Unconjugated (TMAB-01745) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
6. Paraformaldehyde-fixed, paraffin embedded Human Colon Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SNAI1 Polyclonal Antibody, Unconjugated (TMAB-01745) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
7. Paraformaldehyde-fixed, paraffin embedded Human Gastric Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with SNAI1 Polyclonal Antibody, Unconjugated (TMAB-01745) at 1:200 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
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应用IFIHC-FrIHC-PWB
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Note=Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs.
组织特异性Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Anail
抗原种属
Human
基因名称
SNAI1
基因ID
6615
蛋白名称
Zinc finger protein SNAI1
Uniprot ID
O95863
研究领域
Transcription factors,Transcription factors/regulators,Zinc Finger
功能
Involved in the epithelial to mesenchymal transition (EMT) and formation and maintenance of embryonic mesoderm. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.
化学信息
分子量Theoretical: 29 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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