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Anti-MX1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 MX1。Anti-MX1 Polyclonal Antibody 2 可用于 WB。
Anti-MX1 Polyclonal Antibody 2 是一种 Rabbit 抗体,靶向 MX1。Anti-MX1 Polyclonal Antibody 2 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-MX1 Polyclonal Antibody 2 is a Rabbit antibody targeting MX1. Anti-MX1 Polyclonal Antibody 2 can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted, extracellular space. Nucleus. Note=Translocates into the nuclei of HSV-1 infected cells. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | bs-6653P is onesynthetic peptide derived from human MX1. The Dynamin family of microtubule-associated proteins function as GTPases that are involved in microtubule bundling and endocytosis. In mice, Mx2 (myxovirus resistance protein 2) and Mx1 (myxovirus resistance protein 1) are members of the Dynamin family that are involved in the immune response to viral infections. Localized to the cytoplasm, Mx2 contains one GED domain and is expressed in response to viral infection or treatment by IFN-alpha/IFN-beta. Once expression is induced, Mx2 accumulates in the cytoplasm and inhibits the replication of vesicular stomatitis virus (VSV), thereby conferring resistance to VSV infection. Unlike Mx2, Mx1 is localized to the nucleus where, upon induction by IFN-alpha/IFN-beta, it provides selective resistance to infection by the highly lethal H5N1 influenza virus. In humans, MxA and MxB function in a similar manner to Mx1 and Mx2, conferring resistance to specific target viruses. Mx3 is a rat-specific member of the myxovirus resistance protein family. |
| 免疫原 | KLH conjugated synthetic peptide: mouse IFI78/MX1 |
| 抗原种属 | Mouse |
| 基因名称 | MX1 |
| 基因ID | |
| 蛋白名称 | MX dynamin like GTPase 1 |
| 功能 | May regulate the calcium channel activity of TRPCs. Shows activity against influenza virus and VSV, a rhabdovirus. |
| 分子量 | Theoretical: 72 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |