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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-Rb2 p130 (Thr986) Antibody (8C579)

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货号 TMAB-11233

Anti-Phospho-Rb2 p130 (Thr986) Antibody (8C579) 是一种 Rabbit 抗体，靶向 Phospho-Rb2 p130 (Thr986)。Anti-Phospho-Rb2 p130 (Thr986) Antibody (8C579) 可用于 WB,IP。

Anti-Phospho-Rb2 p130 (Thr986) Antibody (8C579)

Anti-Phospho-Rb2 p130 (Thr986) Antibody (8C579)

一键复制产品信息
Rating icon 还可以
货号 TMAB-11233

Anti-Phospho-Rb2 p130 (Thr986) Antibody (8C579) 是一种 Rabbit 抗体，靶向 Phospho-Rb2 p130 (Thr986)。Anti-Phospho-Rb2 p130 (Thr986) Antibody (8C579) 可用于 WB,IP。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-Rb2 p130 (Thr986) Antibody (8C579) is a Rabbit antibody targeting Phospho-Rb2 p130 (Thr986). Anti-Phospho-Rb2 p130 (Thr986) Antibody (8C579) can be used in WB,IP.
Ig Type
IgG
克隆号
8C579
反应种属
Human,Mouse
应用WBIP
推荐剂量
WB: 1:1000-2000; IP: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation.
抗原信息
免疫原
A synthesized peptide: human RBL2 around the phosphorylation site of T986
抗原种属
Human
基因名称
RBL2
基因ID
5934
蛋白名称
Retinoblastoma-like protein 2
Uniprot ID
Q08999
功能
Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.
化学信息
分子量Theoretical: 128 kDa. Actual: 128 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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