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Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442)
还可以产品编号 TMAY-02914
Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) 是一种 Chimera 抗体，靶向 Influenza A H10N8 Hemagglutinin/HA。Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) 可用于 HemagglutininInhibition(HI)。
Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442)
Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442)
还可以产品编号 TMAY-02914
Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) 是一种 Chimera 抗体，靶向 Influenza A H10N8 Hemagglutinin/HA。Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) 可用于 HemagglutininInhibition(HI)。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 200 μg | ¥ 1,985 | 5日内发货 | |
| 500 μg | ¥ 2,990 | 5日内发货 |
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| 产品描述 | Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) is a Chimera antibody targeting Influenza A H10N8 Hemagglutinin/HA. Anti-Influenza A H10N8 Hemagglutinin/HA Antibody (5E442) can be used in HemagglutininInhibition(HI). |
| Ig Type | Monoclonal mouse (varialbe region) / human (kappa / IgG1 constant) chimeric antibody |
| 克隆号 | 5E442 |
| 验证活性 | The neutralization activity of H10N8 HA protein antibody is Measured by Microneutralization test in vitro.The pseudovirus microneutralizaiton (MN) test was performed on 293FT cells infected with H10N8 (A/Jiangxi-Donghu/346/2013) pseudovirus under the treatment of serial dilution of Neutralizing Antibody. The inhibition is 99.3% under 1 μg/mL influenza A H10N8 HA Neutralizing Antibody with high titer H10N8 pseduotype virus. |
| 应用 | HemagglutininInhibition(HI) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Chimera |
| 构建方式 | It is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified, recombinant Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin / HA. The antibody was produced using recombinant antibody technology. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Influenza A H10N8 (A/Jiangxi-Donghu/346/2013) Hemagglutinin / HA protein (TMPY-02662) |
| 抗原种属 | H10N8 |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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