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Anti-Integrin alpha 2 Antibody (2R979) 是一种 Rabbit 抗体,靶向 Integrin alpha 2。Anti-Integrin alpha 2 Antibody (2R979) 可用于 WB,ICC/IF,IHC,IP,FCM。
Anti-Integrin alpha 2 Antibody (2R979) 是一种 Rabbit 抗体,靶向 Integrin alpha 2。Anti-Integrin alpha 2 Antibody (2R979) 可用于 WB,ICC/IF,IHC,IP,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-Integrin alpha 2 Antibody (2R979) is a Rabbit antibody targeting Integrin alpha 2. Anti-Integrin alpha 2 Antibody (2R979) can be used in WB,ICC/IF,IHC,IP,FCM. |
别名 | VLA2 alpha chain, VLA 2 subunit alpha, VLA 2 alpha chain, VLA 2, Very late activation protein 2 receptor alpha 2 subunit, Platelet receptor for collagen, deficiency of, included, Platelet membrane glycoprotein Ia, Platelet glycoprotein Ia/Iia, Platelet glycoprotein Ia, Platelet glycoprotein GPIa, Platelet antigen Br, Platelet alloantigen Br(a), included, Itga2, ITA2, HPA5 included, HPA 5 included, GPIa, GP Ia deficiency, included, GP Ia, Glycoprotein Ia deficiency included, DX5, Collagen receptor, CD49b antigen, CD49b, CD49 antigen like family member B, CD 49b |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
应用 | |
推荐剂量 | WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:100-500; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The sixteen α and eight β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as fibrinogen, or to counter-receptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. Integrin α2 is responsible for adhesion of platelets and other cells to collagens. Modulation of collagen and collagenase gene expression force generation and organization of newly synthesized extracellular matrix. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 150 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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