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别名 度戈妥珠单抗, RG 7597, MEHD-7945A, Duligotumab
Duligotuzumab 是一种双靶向人IgG1单克隆抗体,可同时结合表皮生长因子受体(EGFR)和人表皮生长因子受体3(HER3)。其通过阻断这两种信号通路并诱导抗体依赖性细胞毒性(ADCC)发挥抗肿瘤作用,靶向治疗由EGFR/HER3过表达相关的肿瘤。
Duligotuzumab 是一种双靶向人IgG1单克隆抗体,可同时结合表皮生长因子受体(EGFR)和人表皮生长因子受体3(HER3)。其通过阻断这两种信号通路并诱导抗体依赖性细胞毒性(ADCC)发挥抗肿瘤作用,靶向治疗由EGFR/HER3过表达相关的肿瘤。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 1 mg | ¥ 3,980 | 现货 | |
| 5 mg | ¥ 10,370 | 现货 | |
| 10 mg | ¥ 16,600 | 现货 |
Duligotuzumab 相关产品
| 产品描述 | Duligotuzumab is a dual-targeting human IgG1 monoclonal antibody that simultaneously binds to both epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3). Duligotuzumab exerts its antitumor effects by blocking these dual signaling pathways and by inducing antibody-dependent cellular cytotoxicity (ADCC), targeting tumors where EGFR/HER3 overexpression correlates with poor prognosis. |
| 别名 | 度戈妥珠单抗, RG 7597, MEHD-7945A, Duligotumab |
| 交叉反应 | Human |
| 应用 | ELISA FACS Functional assay |
| 抗体种类 | Monoclonal |
| 宿主来源 | < 1.0 EU/mg |
| 偶联 | Unconjugated |
| CAS No. | 1314238-96-4 |
| 存储 | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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