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顶部生物活性储存和溶解信息计算器

Anti-USP11 Antibody (1W222)

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Anti-USP11 Antibody (1W222)
产品编号 TMAC-04202
别名 USP 11, UHX1, UBP11_HUMAN, Ubiquitin-specific-processing protease 11, Ubiquitin thiolesterase 11, Ubiquitin specific protease 11, ubiquitin specific peptidase 11, Ubiquitin carboxyl-terminal hydrolase X linked, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11

Anti-USP11 Antibody (1W222) 是一种 Rabbit 抗体，靶向 USP11。Anti-USP11 Antibody (1W222) 可用于 WB,ICC/IF,IP,FCM。

Anti-USP11 Antibody (1W222)

Anti-USP11 Antibody (1W222)

Rating icon 还可以
Anti-USP11 Antibody (1W222)
产品编号 TMAC-04202 别名 USP 11, UHX1, UBP11_HUMAN, Ubiquitin-specific-processing protease 11, Ubiquitin thiolesterase 11, Ubiquitin specific protease 11, ubiquitin specific peptidase 11, Ubiquitin carboxyl-terminal hydrolase X linked, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11

Anti-USP11 Antibody (1W222) 是一种 Rabbit 抗体，靶向 USP11。Anti-USP11 Antibody (1W222) 可用于 WB,ICC/IF,IP,FCM。

规格价格库存数量
50 μL
¥ 1,490
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100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-USP11 Antibody (1W222) is a Rabbit antibody targeting USP11. Anti-USP11 Antibody (1W222) can be used in WB,ICC/IF,IP,FCM.
别名USP 11, UHX1, UBP11_HUMAN, Ubiquitin-specific-processing protease 11, Ubiquitin thiolesterase 11, Ubiquitin specific protease 11, ubiquitin specific peptidase 11, Ubiquitin carboxyl-terminal hydrolase X linked, Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of USP11 on 293T cell using anti-USP11 antibody at 1/1,000 dilution.
2. ICC staining USP11 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining USP11 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining USP11 in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. Flow cytometric analysis of Jurkat cells with USP11 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
应用
WB
ICC/IF
IP
FCM
推荐剂量
WB: 1:500-1000; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP11 (ubiquitin specific peptidase 11), also known as UHX1, is a 920 amino acid deubiquitinating enzyme that participates in the Ub pathway. Localized to the nucleus, USP11 associates with both Ran BP-M (Ran binding protein M) and with the tumor suppressor BRCA2. Through these associations, USP11 functions to either inhibit ubiquitination of these proteins or to remove ubiquitin residues that have already been attached to these proteins. USP11 is implicated in several X-linked retinal diseases and, due to its ability to deubiquitinate BRCA2, may play a role in tumor suppression.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P51784
化学信息
分子量Theoretical: 110 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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